Significance of the orexinergic system in modulating stress-related responses in an animal model of post-traumatic stress disorder
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چکیده
منابع مشابه
Stress-induced increases in avoidance responding: an animal model of post-traumatic stress disorder behavior?
One prominent symptom of post-traumatic stress disorder (PTSD) is avoidance of stimuli reminiscent of the traumatic event. We attempted to study this aspect of PTSD in two experiments. Groups of rats received forty 3-s tailshocks, or served as home cage controls (HCC). Twenty-four hours later, all subjects received a 4-h session of leverpress escape/avoidance conditioning. In Experiment 1, shoc...
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Posttraumatic stress disorder (PTSD) is a disorder of emotional and mental stress occurring as an outcome of injury or severe emotional shock. Several Neuroimaging studies in humans have shown the functions and relationship between the anatomical changes of brain and PTSD. The three major areas of the brain are affected by PTSD .These three areas are the amygdala, hippocampus and prefrontal cor...
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Background: Chronic diseases affect the lives of the patient and caregiver. Caring for a patient with a chronic psychiatric illness, such as bipolar disorder, is a stressful and challenging activity. Caregivers of severe psychiatric patients are the primary victims of violence by patients. Caring for these patients can be very stressful for the caregiver to the extent of experiencing post-traum...
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Post-traumatic stress disorder (PTSD) is an increasingly recognized and theoretically preventable condition. In fact PTSD is a mental disorder that can develop after a person is exposed to a traumatic event or threats, such as war and traffic crashes. Symptoms may include distressing thoughts and increased arousal. These signs last for more than one month after the event. People with PTSD are a...
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Introduction: Recent developments in the use of mobile technologies have given rise to opportunities for more effective and cost-efficient services for people with chronic diseases. Considering the relatively high prevalence of post-traumatic stress disorder (PTSD) in Iran and the lack of a native application for the self-management of many complications of this disorder, the present study aims...
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ژورنال
عنوان ژورنال: Translational Psychiatry
سال: 2020
ISSN: 2158-3188
DOI: 10.1038/s41398-020-0698-9